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POLR2A/RPB1 anticorps (pSer1619)

POLR2A Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5959398
  • Antigène Voir toutes POLR2A/RPB1 (POLR2A) Anticorps
    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
    Épitope
    • 17
    • 16
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1619
    Reactivité
    • 89
    • 47
    • 39
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Singe
    Hôte
    • 72
    • 17
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 55
    • 37
    Polyclonal
    Conjugué
    • 54
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    Cet anticorp POLR2A/RPB1 est non-conjugé
    Application
    • 49
    • 25
    • 23
    • 20
    • 12
    • 10
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    DNA directed RNA polymerase II A,DNA-directed RNA polymerase II largest subunit RNA polymerase II 220 kd subunit,DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,hRPB220,hsRPB1,POLR2,Polr2a,POLRA,Polymerase (RNA) II (DNA directed) polypeptide A 220  kDa,Polymerase (RNA) II (DNA directed) polypeptide A,RNA polymerase II subunit B1,RNA-directed RNA polymerase II subunit RPB1,RPB1,RPB1,RPBh1,RpIILS,RPO2,RPOL2
    Purification
    Affinity purification
    Immunogène
    Synthesized peptide derived from human Rpb1 around the phosphorylation site of Ser1619
    Isotype
    IgG
    Top Product
    Discover our top product POLR2A Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
    Autre désignation
    Rpb1 (POLR2A Produits)
    Synonymes
    anticorps NCU02103.1, anticorps 19.m02399, anticorps POLR2A, anticorps 220kDa, anticorps Rpb1, anticorps Rpo2-1, anticorps POLR2, anticorps POLRA, anticorps RPB1, anticorps RPBh1, anticorps RPO2, anticorps RPOL2, anticorps RpIILS, anticorps hRPB220, anticorps hsRPB1, anticorps DNA-directed RNA polymerase II largest subunit, anticorps DNA-directed RNA polymerase II subunit RPB1, anticorps RNA polymerase II large subunit Rpb1, anticorps RNA polymerase II subunit A, anticorps DNA-directed RNA polymerase II largest subunit, putative, anticorps polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, anticorps polymerase (RNA) II (DNA directed) polypeptide A, anticorps NCU02103, anticorps BBOV_I003360, anticorps EDI_169920, anticorps CMU_000800, anticorps SJAG_01713, anticorps MGYG_01527, anticorps POLR2A, anticorps TP03_0185, anticorps EBI_22514, anticorps CGB_E5020W, anticorps polr2a, anticorps Polr2a
    Sujet
    This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
    Poids moléculaire
    217kDa
    ID gène
    5430
    UniProt
    P24928
    Pathways
    Regulatory RNA Pathways
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