ASAH1 anticorps (AA 140-389)

N° du produit ABIN6137159

Détail du produit anti-ASAH1 anticorps

Antigène: ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))

Épitope: AA 140-389

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASAH1 est non-conjugé

Application: Western Blotting (WB)

Séquence: IVAEDKKGHL IHGRNMDFGV FLGWNINNDT WVITEQLKPL TVNLDFQRNN KTVFKASSFA GYVGMLTGFK PGLFSLTLNE RFSINGGYLG ILEWILGKKD VMWIGFLTRT VLENSTSYEE AKNLLTKTKI LAPAYFILGG NQSGEGCVIT RDRKESLDVY ELDAKQGRWY VVQTNYDRWK HPFFLDDRRT PAKMCLNRTS QENISFETMY DVLSTKPVLN KLTVYTTLID VTKGQFETYL RDCPDPCIGW

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 140-389 of human ASAH1 (NP_001120977.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ASAH1

Antigène: ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))

Autre désignation: ASAH1 (ASAH1 Produits)

Synonymes: anticorps AC, anticorps ACDase, anticorps ASAH, anticorps PHP, anticorps PHP32, anticorps SMAPME, anticorps 2310081N20Rik, anticorps Asah, anticorps MGC82286, anticorps asah1, anticorps zgc:101637, anticorps ASAH1, anticorps zgc:66026, anticorps N-acylsphingosine amidohydrolase 1, anticorps N-acylsphingosine amidohydrolase (acid ceramidase) 1, anticorps N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog, anticorps N-acylsphingosine amidohydrolase (acid ceramidase) 1a, anticorps Acid ceramidase, anticorps N-acylsphingosine amidohydrolase (acid ceramidase) 1b, anticorps ASAH1, anticorps Asah1, anticorps asah1.L, anticorps asah1a, anticorps asah-1, anticorps asah1b

Sujet: This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy.,ASAH1,AC,ACDase,ASAH,PHP,PHP32,SMAPME,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,ASAH1

Poids moléculaire: 44 kDa/46 kDa

ID gène: 427

UniProt: Q13510