B4GALT1 anticorps (AA 50-215)

N° du produit ABIN6137403

Détail du produit anti-B4GALT1 anticorps

Antigène: B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))

Épitope: AA 50-215

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp B4GALT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LPQLVGVSTP LQGGSNSAAA IGQSSGELRT GGARPPPPLG ASSQPRPGGD SSPVVDSGPG PASNLTSVPV PHTTALSLPA CPEESPLLVG PMLIEFNMPV DLELVAKQNP NVKMGGRYAP RDCVSPHKVA IIIPFRNRQE HLKYWLYYLH PVLQRQQLDY GIYVIN

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 50-215 of human B4GALT1 (NP_001488.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur B4GALT1

Antigène: B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))

Autre désignation: B4GALT1 (B4GALT1 Produits)

Synonymes: anticorps B4GAL-T1, anticorps CDG2D, anticorps GGTB2, anticorps GT1, anticorps GTB, anticorps beta4Gal-T1, anticorps B-1,4-GalT, anticorps B-1,4-GalT1, anticorps GalT, anticorps Ggtb, anticorps Ggtb2, anticorps b4Gal-T1, anticorps beta-1,4-GalT, anticorps beta-1,4-GalT1, anticorps beta-1,4-galactosyltransferase 1, anticorps UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, anticorps B4GALT1, anticorps B4galt1

Sujet: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.,B4GALT1,B4GAL-T1,CDG2D,GGTB2,GT1,GTB,beta4Gal-T1,beta-1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Angiogenesis,B4GALT1

Poids moléculaire: 42 kDa/43 kDa

ID gène: 2683

UniProt: P15291

Pathways: Glycosaminoglycan Metabolic Process