CHRNG anticorps (AA 328-517)

N° du produit ABIN6138600

Détail du produit anti-CHRNG anticorps

Antigène: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Épitope: AA 328-517

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNG est non-conjugé

Application: Western Blotting (WB)

Séquence: NVSLRSPHTH SMARGVRKVF LRLLPQLLRM HVRPLAPAAV QDTQSRLQNG SSGWSITTGE EVALCLPRSE LLFQQWQRQG LVAAALEKLE KGPELGLSQF CGSLKQAAPA IQACVEACNL IACARHQQSH FDNGNEEWFL VGRVLDRVCF LAMLSLFICG TAGIFLMAHY NRVPALPFPG DPRPYLPSPD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 328-517 of human CHRNG (NP_005190.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CHRNG

Antigène: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Autre désignation: CHRNG (CHRNG Produits)

Synonymes: anticorps ACHRG, anticorps Achr-3, anticorps Acrg, anticorps cholinergic receptor nicotinic gamma subunit, anticorps cholinergic receptor, nicotinic gamma L homeolog, anticorps cholinergic receptor, nicotinic, gamma, anticorps cholinergic receptor, nicotinic gamma, anticorps cholinergic receptor, nicotinic, gamma polypeptide, anticorps CHRNG, anticorps chrng.L, anticorps Chrng, anticorps chrng

Sujet: The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.,CHRNG,ACHRG,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNG

Poids moléculaire: 52 kDa/57 kDa

ID gène: 1146

UniProt: P07510