CIDEA anticorps (AA 20-219)

N° du produit ABIN6138621

Détail du produit anti-CIDEA anticorps

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Épitope: AA 20-219

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEA est non-conjugé

Application: Immunofluorescence (IF)

Séquence: SQTKRVLFTP LMHPARPFRV SNHDRSSRRG VMASSLQELI SKTLDALVIA TGLVTLVLEE DGTVVDTEEF FQTLGDNTHF MILEKGQKWM PGSQHVPTCS PPKRSGIARV TFDLYRLNPK DFIGCLNVKA TMYEMYSVSY DIRCTGLKGL LRSLLRFLSY SAQVTGQFLI YLGTYMLRVL DDKEERPSLR SQAKGRFTCG

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 20-219 of human CIDEA (NP_001270.1).

Isotype: IgG

Information d'application

Indications d'application: IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CIDEA

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Autre désignation: CIDEA (CIDEA Produits)

Synonymes: anticorps CIDE-A, anticorps AW212747, anticorps CIDEA, anticorps cide-a, anticorps MGC89985, anticorps cell death-inducing DFFA-like effector a, anticorps cell death-inducing DNA fragmentation factor, alpha subunit-like effector A, anticorps cell death-inducing DFFA-like effector a L homeolog, anticorps CIDEA, anticorps Cidea, anticorps cidea, anticorps cidea.L

Sujet: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.,CIDEA,CIDE-A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,Cardiovascular,Heart,Lipids,Fatty Acids,CIDEA

Poids moléculaire: 24 kDa

ID gène: 1149

UniProt: O60543