CST3 anticorps (AA 27-146)

N° du produit ABIN6139150

Détail du produit anti-CST3 anticorps

Antigène: CST3 (Cystatin C (CST3))

Épitope: AA 27-146

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CST3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: SSPGKPPRLV GGPMDASVEE EGVRRALDFA VGEYNKASND MYHSRALQVV RARKQIVAGV NYFLDVELGR TTCTKTQPNL DNCPFHDQPH LKRKAFCSFQ IYAVPWQGTM TLSKSTCQDA

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 27-146 of human Cystatin C (NP_000090.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CST3

Antigène: CST3 (Cystatin C (CST3))

Autre désignation: CST3 (CST3 Produits)

Synonymes: anticorps armd11, anticorps fb51d07, anticorps wu:fb24g06, anticorps wu:fb51d07, anticorps wu:fc55f03, anticorps zgc:136227, anticorps ARMD11, anticorps CysC, anticorps CYSC, anticorps cystatin C, anticorps cystatin C L homeolog, anticorps cystatin C (amyloid angiopathy and cerebral hemorrhage), anticorps cystatin 3, anticorps CST3, anticorps cst3.L, anticorps cst3, anticorps cystatin 3, anticorps Cst3

Sujet: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein.,CST3,ARMD11,HEL-S-2,Cell Biology & Developmental Biology,Apoptosis,Caspases,Neuroscience,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,Stem Cells,Neural Stem Cells,Cardiovascular,CST3

Poids moléculaire: 15 kDa

ID gène: 1471

UniProt: P01034