CYP3A5 anticorps (AA 233-502)

N° du produit ABIN6139354

Détail du produit anti-CYP3A5 anticorps

Antigène: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Épitope: AA 233-502

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP3A5 est non-conjugé

Application: Western Blotting (WB)

Séquence: FEALNVSLFP KDTINFLSKS VNRMKKSRLN DKQKHRLDFL QLMIDSQNSK ETESHKALSD LELAAQSIIF IFAGYETTSS VLSFTLYELA THPDVQQKLQ KEIDAVLPNK APPTYDAVVQ MEYLDMVVNE TLRLFPVAIR LERTCKKDVE INGVFIPKGS MVVIPTYALH HDPKYWTEPE EFRPERFSKK KDSIDPYIYT PFGTGPRNCI GMRFALMNMK LALIRVLQNF SFKPCKETQI PLKLDTQGLL QPEKPIVLKV DSRDGTLSGE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 233-502 of human CYP3A5 (NP_000768.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CYP3A5

Antigène: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Autre désignation: CYP3A5 (CYP3A5 Produits)

Synonymes: anticorps CP35, anticorps CYPIIIA5, anticorps P450PCN3, anticorps PCN3, anticorps cytochrome P450 family 3 subfamily A member 5, anticorps CYP3A5

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.,CYP3A5,CP35,CYPIIIA5,P450PCN3,PCN3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP3A5

Poids moléculaire: 15 kDa/57 kDa

ID gène: 1577

UniProt: P20815

Pathways: Steroid Hormone Biosynthesis