Desmocollin 2 anticorps (AA 520-690)

N° du produit ABIN6139827

Détail du produit anti-Desmocollin 2 anticorps

Antigène: Desmocollin 2 (DSC2)

Épitope: AA 520-690

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmocollin 2 est non-conjugé

Application: Western Blotting (WB)

Séquence: IDENTGSIKV FRSLDREAET IKNGIYNITV LASDQGGRTC TGTLGIILQD VNDNSPFIPK KTVIICKPTM SSAEIVAVDP DEPIHGPPFD FSLESSTSEV QRMWRLKAIN DTAARLSYQN DPPFGSYVVP ITVRDRLGMS SVTSLDVTLC DCITENDCTH RVDPRIGGGG V

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 520-690 of human DSC2 (NP_077740.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Desmocollin 2

Antigène: Desmocollin 2 (DSC2)

Autre désignation: DSC2 (DSC2 Produits)

Synonymes: anticorps ARVD11, anticorps CDHF2, anticorps DG2, anticorps DGII/III, anticorps DSC3, anticorps AW228162, anticorps Dsc2a, anticorps Dsc2b, anticorps DSC2, anticorps desmocollin 2, anticorps DSC2, anticorps Dsc2

Sujet: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.,DSC2,ARVD11,CDHF2,DG2,DGII/III,DSC3,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Extracellular Matrix,Cardiovascular,Heart,Cardiac arrhythmias,DSC2

Poids moléculaire: 93 kDa/99 kDa

ID gène: 1824

UniProt: Q02487