EIF3B anticorps

N° du produit ABIN6989663

Détail du produit anti-EIF3B anticorps

Antigène: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF3B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Synthetic Peptide within N terminal human eIF3B.

Clone: 5H10

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur EIF3B

Antigène: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Autre désignation: eIF3B (EIF3B Produits)

Synonymes: anticorps EIF3-ETA, anticorps EIF3-P110, anticorps EIF3-P116, anticorps EIF3S9, anticorps PRT1, anticorps AL033316, anticorps AL033334, anticorps AL033369, anticorps AW208965, anticorps D5Wsu45e, anticorps Eif3s9, anticorps eif3-eta, anticorps eif3-p110, anticorps eif3-p116, anticorps eif3s9, anticorps prt1, anticorps ATEIF3B-2, anticorps EIF3B, anticorps EUKARYOTIC TRANSLATION INITIATION FACTOR 3B, anticorps F18A17.30, anticorps F18A17_30, anticorps eukaryotic translation initiation factor 3B-2, anticorps DDBDRAFT_0218512, anticorps DDBDRAFT_0233929, anticorps DDB_0218512, anticorps DDB_0233929, anticorps eIF-3-eta, anticorps eif3b, anticorps wu:fc17c01, anticorps GB10123, anticorps eIF3b, anticorps AO090005000892, anticorps CaO19.6584, anticorps eIF3 p90, anticorps eukaryotic translation initiation factor 3 subunit B, anticorps eukaryotic translation initiation factor 3, subunit B, anticorps eukaryotic translation initiation factor 3B-2, anticorps eukaryotic initiation factor, anticorps RNA recognition motif-containing protein RRM, anticorps eukaryotic translation initiation factor 3b, anticorps eukaryotic translation initiation factor 3 subunit B L homeolog, anticorps eukaryotic translation initiation factor 3, subunit Ba, anticorps eukaryotic translation initiation factor 3 subunit 9, anticorps translation initiation factor eIF-3 subunit 9, anticorps Eukaryotic translation initiation factor 3 subunit B, anticorps translation initiation factor eIF3 subunit b, anticorps EIF3B, anticorps Eif3b, anticorps eif3b, anticorps EIF3B-2, anticorps eIF3s9, anticorps eif3B, anticorps eif3b.L, anticorps eif3ba, anticorps LOC410100, anticorps eIF3-S9, anticorps AOR_1_1564174, anticorps VDBG_02490, anticorps PGTG_13070, anticorps Tsp_02250, anticorps eif-3.B, anticorps PRT1

Sujet:

Synonyms: eIF-3-eta antibody, eIF3 eta antibody, eIF3 p110 antibody, eIF3 p116 antibody, EIF3-ETA antibody, EIF3-P110 antibody, EIF3-P116 antibody, eIF3b antibody, EIF3B_HUMAN antibody, EIF3S9 antibody, EIF3S9, formerly antibody, Eukaryotic translation initiation factor 3, subunit B antibody, Eukaryotic translation initiation factor 3 subunit 9 antibody, eukaryotic translation initiation factor 3 subunit 9 eta antibody, Eukaryotic translation initiation factor 3 subunit B antibody, eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) antibody, eukaryotic translation initiation factor 3, subunit 9 eta, 116 kDa antibody, eukaryotic translation initiation factor 3, subunit 9, formerly antibody, hPrt1 antibody, Protein synthesis defective at 36 degrees celsius 1, S. cerevisiae, homolog of antibody, PRT1 antibody, Prt1 homolog antibody

Background: eIF3b expression relates to human bladder and prostate cancer prognosis, is required for tumor growth, and thus a candidate therapeutic target.The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. Association of eIF3 proteins with the 40S ribosomal subunit stabilizes eIF2-GTP-Met-tRNAiMet complex association and mRNA binding, and promotes dissociation of 80S ribosomes into 40S and 60S subunits, thereby promoting the assembly of the pre-initiation complex. Overexpression of eIF3 proteins is common in several cancers, suggesting a role for eIF3 proteins in tumorigenesis.

ID gène: 8662

UniProt: P55884

Pathways: Ribonucleoprotein Complex Subunit Organization