HLA-DMA anticorps (AA 27-233)

N° du produit ABIN6141805

Détail du produit anti-HLA-DMA anticorps

Antigène: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Épitope: AA 27-233

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-DMA est non-conjugé

Application: Western Blotting (WB)

Séquence: VPEAPTPMWP DDLQNHTFLH TVYCQDGSPS VGLSEAYDED QLFFFDFSQN TRVPRLPEFA DWAQEQGDAP AILFDKEFCE WMIQQIGPKL DGKIPVSRGF PIAEVFTLKP LEFGKPNTLV CFVSNLFPPM LTVNWQHHSV PVEGFGPTFV SAVDGLSFQA FSYLNFTPEP SDIFSCIVTH EIDRYTAIAY WVPRNALPSD LLENVLC

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 27-233 of human HLA-DMA (NP_006111.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HLA-DMA

Antigène: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Autre désignation: HLA-DMA (HLA-DMA Produits)

Synonymes: anticorps RT1.Ma, anticorps RT1.DMa, anticorps HLA-DMA, anticorps H-2Ma, anticorps H2-Ma, anticorps D6S222E, anticorps DMA, anticorps HLADM, anticorps RING6, anticorps RT1 class II, locus DMa, anticorps SLA-DM alpha chain, anticorps major histocompatibility complex, class II, DM alpha, anticorps histocompatibility 2, class II, locus DMa, anticorps RT1-DMa, anticorps SLA-DMA, anticorps DLA-DMA, anticorps H2-DMa, anticorps HLA-DMA

Sujet: HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.,HLA-DMA,D6S222E,DMA,HLADM,RING6,major histocompatibility complex,class II,DM alpha,Immunology & Inflammation,Cardiovascular,Blood,HLA-DMA

Poids moléculaire: 29 kDa

ID gène: 3108

UniProt: P28067

Pathways: Cancer Immune Checkpoints