Serotonin Receptor 2B anticorps (AA 382-481)

N° du produit ABIN6142069

Cet anticorps anti-Serotonin Receptor 2B est un anticorps Lapin Polyclonal détectant Serotonin Receptor 2B dans WB et IF. Adapté pour Humain.

Aperçu rapide pour Serotonin Receptor 2B anticorps (AA 382-481) (ABIN6142069)

Antigène: Serotonin Receptor 2B (HTR2B)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 2B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Serotonin Receptor 2B anticorps

Épitope: AA 382-481

Séquence: LFNKTFRDAF GRYITCNYRA TKSVKTLRKR SSKIYFRNPM AENSKFFKKH GIRNGINPAM YQSPMRLRSS TIQSSSIILL DTLLLTENEG DKTEEQVSYV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 382-481 of human HTR2B (NP_000858.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:10 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Serotonin Receptor 2B

Antigène: Serotonin Receptor 2B (HTR2B)

Autre désignation: HTR2B

Sujet: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.,HTR2B,5-HT(2B),5-HT-2B,5-HT2B,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,HTR2B

Poids moléculaire: 54 kDa

ID gène: 3357

UniProt: P41595

Pathways: Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process