KCNJ3 anticorps (AA 50-150)

N° du produit ABIN6142731

Détail du produit anti-KCNJ3 anticorps

Antigène: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Épitope: AA 50-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: NGRCNVQHGN LGSETSRYLS DLFTTLVDLK WRWNLFIFIL TYTVAWLFMA SMWWVIAYTR GDLNKAHVGN YTPCVANVYN FPSAFLFFIE TEATIGYGYR Y

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KCNJ3 (NP_002230.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KCNJ3

Antigène: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Autre désignation: KCNJ3 (KCNJ3 Produits)

Synonymes: anticorps GIRK1, anticorps KGA, anticorps KIR3.1, anticorps Kcnf3, anticorps Kir3.1, anticorps girk1, anticorps potassium voltage-gated channel subfamily J member 3, anticorps potassium inwardly-rectifying channel, subfamily J, member 3, anticorps KCNJ3, anticorps Kcnj3

Sujet: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins.,KCNJ3,GIRK1,KGA,KIR3.1,Neuroscience,Cardiovascular,Heart,Cardiac arrhythmias,KCNJ3

Poids moléculaire: 26 kDa/56 kDa

ID gène: 3760

UniProt: P48549