Laminin beta 1 anticorps (AA 1467-1786)

N° du produit ABIN6143068

Détail du produit anti-Laminin beta 1 anticorps

Antigène: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Épitope: AA 1467-1786

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Laminin beta 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: EAKLRADEAK QSAEDILLKT NATKEKMDKS NEELRNLIKQ IRNFLTQDSA DLDSIEAVAN EVLKMEMPST PQQLQNLTED IRERVESLSQ VEVILQHSAA DIARAEMLLE EAKRASKSAT DVKVTADMVK EALEEAEKAQ VAAEKAIKQA DEDIQGTQNL LTSIESETAA SEETLFNASQ RISELERNVE ELKRKAAQNS GEAEYIEKVV YTVKQSAEDV KKTLDGELDE KYKKVENLIA KKTEESADAR RKAEMLQNEA KTLLAQANSK LQLLKDLERK YEDNQRYLED KAQELARLEG EVRSLLKDIS QKVAVYSTCL

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1467-1786 of human Laminin beta 1 (NP_002282.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:4000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Laminin beta 1

Antigène: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Autre désignation: LAMB1 (LAMB1 Produits)

Synonymes: anticorps CLM, anticorps LIS5, anticorps fc20b05, anticorps gup, anticorps lamb1, anticorps sb:cb95, anticorps wu:fc20b05, anticorps Lamb1-1, anticorps LAMB1, anticorps C77966, anticorps C80098, anticorps C81607, anticorps D130003D08Rik, anticorps Lamb-1, anticorps laminin subunit beta 1, anticorps laminin, beta 1a, anticorps laminin B1, anticorps LAMB1, anticorps lamb1a, anticorps Lamb1, anticorps lamb1

Sujet: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.,LAMB1,CLM,LIS5,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Cardiovascular,Angiogenesis,LAMB1

Poids moléculaire: 198 kDa

ID gène: 3912

UniProt: P07942