MSH3 anticorps (AA 617-761)

N° du produit ABIN6144059

Détail du produit anti-MSH3 anticorps

Antigène: MSH3 (MutS Homolog 3 (MSH3))

Épitope: AA 617-761

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSH3 est non-conjugé

Application: Western Blotting (WB)

Séquence: FNTSEEHHAD MYRSDLPNPD TLSAELHCWR IKWKHRGKDI ELPSTIYEAL HLPDIKFFPN VYALLKVLCI LPVMKVENER YENGRKRLKA YLRNTLTDQR SSNLALLNIN FDIKHDLDLM VDTYIKLYTS KSELPTDNSE TVENT

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 617-761 of human MSH3 (NP_004696.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MSH3

Antigène: MSH3 (MutS Homolog 3 (MSH3))

Autre désignation: MSH3 (MSH3 Produits)

Synonymes: anticorps ATMSH3, anticorps M7J2.90, anticorps M7J2_90, anticorps homolog of DNA mismatch repair protein MSH3, anticorps DUP, anticorps MRP1, anticorps D13Em1, anticorps Rep-3, anticorps Rep3, anticorps mutS homolog 3, anticorps DNA mismatch repair protein MSH3, anticorps homolog of DNA mismatch repair protein MSH3, anticorps mismatch repair protein, anticorps MSH3, anticorps Msh3

Sujet: The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.,MSH3,DUP,FAP4,MRP1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MSH3

Poids moléculaire: 127 kDa

ID gène: 4437

UniProt: P20585

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response