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TNF alpha anticorps
TNF alpha
Reactivité: Humain
WB, Func, EIA
Hôte: Souris
Monoclonal
MAb1
unconjugated
Détail du produit anti-TNF alpha anticorps
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Antigène
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TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Reactivité
Toutes les réactivités sur TNF alpha Anticorps
Humain
Hôte
Toutes les hôtes sur TNF alpha Anticorps
Souris
Clonalité
Toutes les clonalités sur TNF alpha Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers TNF alpha Anticorps
Cet anticorp TNF alpha est non-conjugé
Application
Tous les applications à travers TNF alpha Anticorps.
Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)
Specificité
This antibody recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha).
Purification
Affinity Chromatography
Immunogène
Human TNF
Clone
MAb1
Isotype
IgG1
Top Product
Discover our top product TNF alpha Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Buffer
PBS, pH 7.4, 0.09 % Sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C.
Détails sur TNF alpha
(cache)
Antigène
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Autre désignation
Tumor Necrosis Factor (TNF-Alpha) (TNF alpha Produits )
Synonymes
anticorps DIF, anticorps TNF-alpha, anticorps TNFA, anticorps TNFSF2, anticorps RATTNF, anticorps Tnfa, anticorps tnf, anticorps TNF-a, anticorps TNFalpha, anticorps Tnfsf1a, anticorps TNFa, anticorps cTNF, anticorps Tnf-alpha, anticorps tnfa-like, anticorps TNF-ALPHA, anticorps dif, anticorps tnfa, anticorps xtnf, anticorps tnfsf2, anticorps tnf-alpha, anticorps Cachectin, anticorps tumor necrosis factor, anticorps tumor necrosis factor b (TNF superfamily, member 2), anticorps tumor necrosis factor alpha, anticorps tumor necrosis factor a (TNF superfamily, member 2), anticorps TNF, anticorps Tnf, anticorps tnf, anticorps tnfb, anticorps tnf-alpha, anticorps LOC103694380, anticorps tnfa
Sujet
TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
ID gène
7124
NCBI Accession
NP_000585
UniProt
P01375
Pathways
Signalisation NF-kappaB , Apoptose , Caspase Cascade in Apoptosis , Signalisation TLR , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
Vus récemment
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