PCSK1 anticorps (AA 604-753)

N° du produit ABIN6145322

Détail du produit anti-PCSK1 anticorps

Antigène: PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))

Épitope: AA 604-753

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCSK1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: PRVYTSYNTV QNDRRGVEKM VDPGEEQPTQ ENPKENTLVS KSPSSSSVGG RRDELEEGAP SQAMLRLLQS AFSKNSPPKQ SPKKSPSAKL NIPYENFYEA LEKLNKPSQL KDSEDSLYND YVDVFYNTKP YKHRDDRLLQ ALVDILNEEN

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 604-753 of human PCSK1 (NP_000430.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PCSK1

Antigène: PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))

Autre désignation: PCSK1 (PCSK1 Produits)

Synonymes: anticorps BMIQ12, anticorps NEC1, anticorps PC1, anticorps PC3, anticorps SPC3, anticorps Nec-1, anticorps Nec1, anticorps Phpp-1, anticorps BDP, anticorps PC1/3, anticorps proprotein convertase subtilisin/kexin type 1, anticorps prohormone convertase 1, anticorps PCSK1, anticorps Pcsk1, anticorps pcsk1, anticorps PC1B

Sujet: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene,PCSK1,BMIQ12,NEC1,PC1,PC3,SPC3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Ubiquitin,Endocrine & Metabolism,Neuroscience,PCSK1

Poids moléculaire: 79 kDa/84 kDa

ID gène: 5122

UniProt: P29120

Pathways: Peptide Hormone Metabolism