POLD3 anticorps (AA 197-466)

N° du produit ABIN6145881

Détail du produit anti-POLD3 anticorps

Antigène: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Épitope: AA 197-466

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLD3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: ASKAAAKTQE TNKETKTEAK EVTNASAAGN KAPGKGNMMS NFFGKAAMNK FKVNLDSEQA VKEEKIVEQP TVSVTEPKLA TPAGLKKSSK KAEPVKVLQK EKKRGKRVAL SDDETKETEN MRKKRRRIKL PESDSSEDEV FPDSPGAYEA ESPSPPPPPS PPLEPVPKTE PEPPSVKSSS GENKRKRKRV LKSKTYLDGE GCIVTEKVYE SESCTDSEEE LNMKTSSVHR PPAMTVKKEP REERKGPKKG TAALGKANRQ VSITGFFQRK

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 197-466 of human POLD3 (NP_006582.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-POLD3 (ABIN6145881)

Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." dans: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

Détails sur POLD3

Antigène: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Autre désignation: POLD3 (POLD3 Produits)

Synonymes: anticorps zgc:136471, anticorps P66, anticorps P68, anticorps 2410142G14Rik, anticorps C85233, anticorps polymerase (DNA-directed), delta 3, accessory subunit L homeolog, anticorps polymerase (DNA-directed), delta 3, accessory subunit, anticorps DNA polymerase delta 3, accessory subunit, anticorps pold3.L, anticorps pold3, anticorps POLD3, anticorps Pold3

Sujet: This gene encodes the 66- kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.,POLD3,P66,P68,PPP1R128,Epigenetics & Nuclear Signaling,DNA Damage & Repair,POLD3

Poids moléculaire: 39 kDa/46 kDa/51 kDa

ID gène: 10714

UniProt: Q15054

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA