PTGS2 anticorps (AA 375-604)

N° du produit ABIN6146415

Détail du produit anti-PTGS2 anticorps

Antigène: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Épitope: AA 375-604

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: PLLPDTFQIH DQKYNYQQFI YNNSILLEHG ITQFVESFTR QIAGRVAGGR NVPPAVQKVS QASIDQSRQM KYQSFNEYRK RFMLKPYESF EELTGEKEMS AELEALYGDI DAVELYPALL VEKPRPDAIF GETMVEVGAP FSLKGLMGNV ICSPAYWKPS TFGGEVGFQI INTASIQSLI CNNVKGCPFT SFSVPDPELI KTVTINASSS RSGLDDINPT VLLKERSTEL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 375-604 of human COX2/PTGS2 (NP_000954.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:4000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-PTGS2 (ABIN6146415)

Dai, Ciccotosto, Cappai, Tang, Li, Xie, Xiao, Velkov: "Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis." dans: Molecular neurobiology, Vol. 55, Issue 1, pp. 421-434, (2018) (PubMed).

Zhang, Li, Li, Liu, Wei, Qian: "Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation." dans: Vascular pharmacology, Vol. 96-98, pp. 26-32, (2017) (PubMed).

Zou, Zhou, Hu, Zhang, Tang, Wen, Xiao, Wang: "Rhizoma Smilacis Glabrae inhibits pathogen-induced upper genital tract inflammation in rats through suppression of NF-κB pathway." dans: Journal of ethnopharmacology, Vol. 202, pp. 103-113, (2017) (PubMed).

Détails sur PTGS2

Antigène: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Autre désignation: PTGS2 (PTGS2 Produits)

Synonymes: anticorps COX-2, anticorps COX2, anticorps GRIPGHS, anticorps PGG/HS, anticorps PGHS-2, anticorps PHS-2, anticorps hCox-2, anticorps Cox-2, anticorps Pghs2, anticorps TIS10, anticorps Cox2, anticorps cox-2, anticorps CEF147, anticorps PGHS2, anticorps PHSII, anticorps cox2, anticorps gripghs, anticorps pgg/hs, anticorps pghs-2, anticorps phs-2, anticorps PTGS2, anticorps hcox-2, anticorps fj02a10, anticorps ptgs2, anticorps unp1239, anticorps wu:fj02a10, anticorps zCOX-2, anticorps si:dkey-97o5.6, anticorps prostaglandin-endoperoxide synthase 2, anticorps prostaglandin G/H synthase 2, anticorps prostaglandin-endoperoxide synthase 2S homeolog, anticorps prostaglandin-endoperoxide synthase 2a, anticorps prostaglandin-endoperoxide synthase 2b, anticorps PTGS2, anticorps Ptgs2, anticorps LOC100136456, anticorps ptgs2.S, anticorps ptgs2, anticorps ptgs2a, anticorps ptgs2b

Sujet: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.,PTGS2,COX-2,COX2,GRIPGHS,PGG/HS,PGHS-2,PHS-2,hCox-2,Cox2,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Blood,Lipids,PTGS2

Poids moléculaire: 68 kDa

ID gène: 5743

UniProt: P35354

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation