PTGS2 anticorps

N° du produit ABIN7180881

Détail du produit anti-PTGS2 anticorps

Antigène: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from Human Cox2.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PTGS2

Antigène: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Autre désignation: PTGS2 (PTGS2 Produits)

Synonymes: anticorps COX-2, anticorps COX2, anticorps GRIPGHS, anticorps PGG/HS, anticorps PGHS-2, anticorps PHS-2, anticorps hCox-2, anticorps Cox-2, anticorps Pghs2, anticorps TIS10, anticorps Cox2, anticorps cox-2, anticorps CEF147, anticorps PGHS2, anticorps PHSII, anticorps cox2, anticorps gripghs, anticorps pgg/hs, anticorps pghs-2, anticorps phs-2, anticorps PTGS2, anticorps hcox-2, anticorps fj02a10, anticorps ptgs2, anticorps unp1239, anticorps wu:fj02a10, anticorps zCOX-2, anticorps si:dkey-97o5.6, anticorps prostaglandin-endoperoxide synthase 2, anticorps prostaglandin G/H synthase 2, anticorps prostaglandin-endoperoxide synthase 2S homeolog, anticorps prostaglandin-endoperoxide synthase 2a, anticorps prostaglandin-endoperoxide synthase 2b, anticorps PTGS2, anticorps Ptgs2, anticorps LOC100136456, anticorps ptgs2.S, anticorps ptgs2, anticorps ptgs2a, anticorps ptgs2b

Sujet:

Background: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

Nathalie Bonnefoy, Mol. Cell. Biol., Apr 2001, 21: 2359 - 2372.
Keith P. Choe, J. Exp. Biol., May 2006, 209: 1696 - 1708
D. Shelley Lupold, PNAS, Sep 1999, 96: 11670.
Axel J. Baumgarten, AACR Meeting Abstracts, Mar 2004, 2004: 1078.

Aliases: COX 2 antibody, COX-2 antibody, COX2 antibody, Cyclooxygenase 2 antibody, Cyclooxygenase 2b antibody, Cyclooxygenase antibody, Cyclooxygenase-2 antibody, Cyclooxygenase2 antibody, EC 1.14.99.1 antibody, fj02a10 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody, Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase antibody, GRIPGHS antibody, hCox 2 antibody, Macrophage activation-associated marker protein P71/73 antibody, OTTHUMP00000033524 antibody, PES-2 antibody, PGG/HS antibody, PGH synthase 2 antibody, PGH2_HUMAN antibody, PGHS 2 antibody, PGHS-2 antibody, PGHS2 antibody, PHS 2 antibody, PHS II antibody, PHS2 antibody, Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) antibody, Prostaglandin endoperoxide synthase 2 antibody, Prostaglandin G/H synthase 2 antibody, Prostaglandin G/H synthase 2 precursor antibody, Prostaglandin G/H synthase and cyclooxygenase antibody, Prostaglandin G/H synthase antibody, Prostaglandin H2 synthase 2 antibody, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) antibody, Prostaglandin-endoperoxide synthase 2 antibody, PTGS2 antibody, ptgs2a antibody, TIS10 antibody, TIS10 protein antibody, unp1239 antibody, wu:fj02a10 antibody

UniProt: P35354

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation