Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ADAM17 anticorps (AA 215-315)

ADAM17 Reactivité: Humain WB, IHC (p), EIA Hôte: Souris Monoclonal 1F6 unconjugated
N° du produit ABIN614668
  • Antigène Voir toutes ADAM17 Anticorps
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Épitope
    • 16
    • 13
    • 13
    • 8
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 215-315
    Reactivité
    • 114
    • 54
    • 52
    • 4
    • 4
    • 4
    • 1
    • 1
    Humain
    Hôte
    • 100
    • 12
    • 2
    • 1
    • 1
    Souris
    Clonalité
    • 92
    • 24
    Monoclonal
    Conjugué
    • 53
    • 11
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADAM17 est non-conjugé
    Application
    • 86
    • 53
    • 40
    • 15
    • 14
    • 14
    • 12
    • 10
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to A Disintegrin And Metalloproteinase Domain 17 (ADAM17/TACE).
    Purification
    Protein A Chromatography
    Immunogène
    Recombinant protein, ADAM17 (NP_003174, 215 a.a. ~ 315 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: ADAM17
    Clone
    1F6
    Isotype
    IgG2b
    Top Product
    Discover our top product ADAM17 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS, pH 7.2
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
  • Antigène
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Autre désignation
    CD156b / ADAM17 (ADAM17 Produits)
    Synonymes
    anticorps ADAM18, anticorps CD156B, anticorps CSVP, anticorps NISBD, anticorps TACE, anticorps CD156b, anticorps Tace, anticorps adam17, anticorps si:dkey-81b15.2, anticorps adam18, anticorps cd156b, anticorps csvp, anticorps tace, anticorps fc20b01, anticorps wu:fc20b01, anticorps zgc:63886, anticorps ADAM metallopeptidase domain 17, anticorps a disintegrin and metallopeptidase domain 17, anticorps ADAM metallopeptidase domain 17b, anticorps ADAM metallopeptidase domain 17 L homeolog, anticorps ADAM metallopeptidase domain 17a, anticorps ADAM17, anticorps Adam17, anticorps adam17b, anticorps adam17.L, anticorps adam17a
    Sujet
    Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGFa, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP). TACE mRNA is expressed in a variety of human and murine tissues. TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association. ADAM17 is a Metallopeptidase M12B type protease.Synonyms: CSVP, Disintegrin and metalloproteinase domain-containing protein 17, Snake venom-like protease, TACE, TNF-alpha convertase, TNF-alpha-converting enzyme
    ID gène
    6868
    NCBI Accession
    NP_003174
    UniProt
    P78536
    Pathways
    Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
Vous êtes ici:
Support technique