RHOA anticorps (C-Term)
Aperçu rapide pour RHOA anticorps (C-Term) (ABIN6146932)
Antigène
Voir toutes RHOA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- KPEEGRDMAN RIGAFGYMEC SAKTKDGVRE VFEMATRAAL QARRGKKKSG CLVL
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 140 to the C-terminus of human RhoA (NP_001655.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RHOA (Ras Homolog Gene Family, Member A (RHOA))
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Autre désignation
- RHOA
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Sujet
- This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.,ARH12,ARHA,RHO12,RHOH12,Rho,RHOA,RhoA,Cancer,Signal Transduction,G protein signaling,Signal Transduction,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microfilaments,Microtubules,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,RHOA
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Poids moléculaire
- 21 kDa
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ID gène
- 387
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UniProt
- P61586
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Pathways
- Dynamique des Microtubules, Signalisation WNT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome
Antigène
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