NR1D1 anticorps (AA 1-615)

N° du produit ABIN614695

Détail du produit anti-NR1D1 anticorps

Antigène: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Épitope: AA 1-615

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NR1D1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Nuclear Receptor Rev-ErbA Alpha (NR1D1).

Purification: Protein A Chromatography

Immunogène: Recombinant protein, NR1D1 (AAH56148, 1 a.a. ~ 615 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: NR1D1

Clone: 4F6

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NR1D1

Antigène: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Autre désignation: NR1D1 (NR1D1 Produits)

Synonymes: anticorps MGC82865, anticorps MGC82881, anticorps Eip75B, anticorps EAR1, anticorps THRA1, anticorps THRAL, anticorps ear-1, anticorps hRev, anticorps A530070C09Rik, anticorps R75201, anticorps REV-ERBAALPHA, anticorps nuclear receptor subfamily 1 group D member 1 L homeolog, anticorps nuclear receptor subfamily 1, group d, member 1, anticorps nuclear receptor subfamily 1 group D member 1, anticorps nuclear receptor subfamily 1, group D, member 1, anticorps nr1d1.L, anticorps nr1d1, anticorps NR1D1, anticorps Nr1d1

Sujet: Rev-erbA alpha, a NR1 Thyroid Hormone-Like Receptor, is encoded by the same genomic locus as, but transcribed from the opposite strand of, Thyroid Hormone Receptor Alpha (TR Alpha). Rev-erbA alpha is a target of Nuclear Receptor ROR Alpha (Delerive et al. 2002), and a transcription regulator that has been shown to affect myocyte differentiation, adipogenesis, and lipoprotein metabolism. Recently Reb-erbA alpha has been shown to affect circadian rhythms by regulating cyclic Bmal1 transcription ( Preitner et al. 2002, Ueda et al. 2002). Mice lacking Rev-erbA alpha show abnormal postnatal cerebellar development.Synonyms: EAR1, HREV, Nuclear receptor subfamily 1 group D member 1, Rev-erbA-alpha, THRAL, V-erbA-related protein EAR-1

ID gène: 9572

NCBI Accession: NP_068370

UniProt: P20393

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha