NR1D1 anticorps

N° du produit ABIN700854

Détail du produit anti-NR1D1 anticorps

Antigène: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR1D1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NR1D1

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Références pour anticorps anti-NR1D1 (ABIN700854)

Zhao, Li, Wei, Savage, Zhou, Ma: "Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring." dans: Neurobiology of disease, Vol. 68, pp. 145-55, (2014) (PubMed).

Détails sur NR1D1

Antigène: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Autre désignation: NR1D1 (NR1D1 Produits)

Synonymes: anticorps MGC82865, anticorps MGC82881, anticorps Eip75B, anticorps EAR1, anticorps THRA1, anticorps THRAL, anticorps ear-1, anticorps hRev, anticorps A530070C09Rik, anticorps R75201, anticorps REV-ERBAALPHA, anticorps nuclear receptor subfamily 1 group D member 1 L homeolog, anticorps nuclear receptor subfamily 1, group d, member 1, anticorps nuclear receptor subfamily 1 group D member 1, anticorps nuclear receptor subfamily 1, group D, member 1, anticorps nr1d1.L, anticorps nr1d1, anticorps NR1D1, anticorps Nr1d1

Sujet:

Synonyms: EAR-1, EAR1, ERBA-RELATED 1, hRev, Nr1d1, NR1D1_HUMAN, Nuclear Receptor Rev-ErbA Alpha, Nuclear receptor subfamily 1 group D member 1, Orphan nuclear receptor NR1D1, Rev erbAalpha, Rev erbalpha, Rev-erbA-alpha, Rev-ErbAalpha, REV-ERBalpha, THRA1, THRAL, Thyroid hormone receptor alpha-like, Thyroid hormone receptor, alpha like, V-erbA related protein EAR-1, V-erbA-related protein 1.

Background: NR1D1, a NR1 Thyroid Hormone-Like Receptor, is encoded by the same genomic locus as, but transcribed from the opposite strand of, Thyroid Hormone Receptor Alpha (TR Alpha). NR1D1 is a target of Nuclear Receptor ROR Alpha and a transcription regulator that has been shown to affect myocyte differentiation, adipogenesis, and lipoprotein metabolism. Mice lacking NR1D1 show abnormal postnatal cerebellar development. NR1D1 expression has been documented in human skeletal muscle and a variety of mouse and rat tissues. ESTs have been isolated from human tissue libraries, including cancerous adrenal, blood, brain, breast, colon, duodenum, fetus, head/neck, kidney, lung, skeletal muscle, skin, synovium, uterus, normal brain, breast, colon, eye, heart, pancreas, pituitary, prostate, skeletal muscle, skin, testis and thyroid.

Poids moléculaire: 68kDa

ID gène: 9572

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha