RUNX1T1 anticorps (AA 100-390)

N° du produit ABIN6147312

Détail du produit anti-RUNX1T1 anticorps

Antigène: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Épitope: AA 100-390

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX1T1 est non-conjugé

Application: Western Blotting (WB)

Séquence: GNDISPEIGE RVRTLVLGLV NSTLTIEEFH SKLQEATNFP LRPFVIPFLK ANLPLLQREL LHCARLAKQN PAQYLAQHEQ LLLDASTTSP VDSSELLLDV NENGKRRTPD RTKENGFDRE PLHSEHPSKR PCTISPGQRY SPNNGLSYQP NGLPHPTPPP PQHYRLDDMA IAHHYRDSYR HPSHRDLRDR NRPMGLHGTR QEEMIDHRLT DREWAEEWKH LDHLLNCIMD MVEKTRRSLT VLRRCQEADR EELNYWIRRY SDAEDLKKGG GSSSSHSRQQ SPVNPDPVAL D

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 100-390 of human RUNX1T1 (NP_783554.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RUNX1T1

Antigène: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Autre désignation: RUNX1T1 (RUNX1T1 Produits)

Synonymes: anticorps MTG8, anticorps si:ch211-232j17.1, anticorps wu:fi14b07, anticorps zgc:154044, anticorps AML1T1, anticorps CBFA2T1, anticorps CDR, anticorps ETO, anticorps ZMYND2, anticorps Cbfa2t1h, anticorps Cbfa2t1, anticorps runt-related transcription factor 1; translocated to, 1 (cyclin D-related), anticorps RUNX1 translocation partner 1 L homeolog, anticorps RUNX1 translocation partner 1, anticorps runx1t1, anticorps runx1t1.L, anticorps RUNX1T1, anticorps Runx1t1

Sujet: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.,RUNX1T1,AML1-MTG8,AML1T1,CBFA2T1,CDR,ETO,MTG8,ZMYND2,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,RUNX1T1

Poids moléculaire: 44 kDa/48 kDa/63 kDa/64 kDa/67 kDa/68 kDa

ID gène: 862

UniProt: Q06455