SAV1 anticorps (AA 1-210)

N° du produit ABIN6147400

Détail du produit anti-SAV1 anticorps

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Épitope: AA 1-210

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAV1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MLSRKKTKNE VSKPAEVQGK YVKKETSPLL RNLMPSFIRH GPTIPRRTDI CLPDSSPNAF STSGDVVSRN QSFLRTPIQR TPHEIMRRES NRLSAPSYLA RSLADVPREY GSSQSFVTEV SFAVENGDSG SRYYYSDNFF DGQRKRPLGD RAHEDYRYYE YNHDLFQRMP QNQGRHASGI GRVAATSLGN LTNHGSEDLP LPPGWSVDWT

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SAV1 (NP_068590.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:4000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SAV1

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Autre désignation: SAV1 (SAV1 Produits)

Synonymes: anticorps SAV, anticorps WW45, anticorps WWP4, anticorps 1700040G09Rik, anticorps Salv, anticorps Sav, anticorps Wwp3, anticorps Wwp4, anticorps salvador family WW domain containing protein 1, anticorps salvador family WW domain containing 1, anticorps SAV1, anticorps Sav1

Sujet: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.,SAV1,SAV,WW45,WWP4,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Hippo Signaling Pathway,SAV1

Poids moléculaire: 44 kDa

ID gène: 60485

UniProt: Q9H4B6

Pathways: Stem Cell Maintenance