SLAMF7 anticorps (AA 23-226)

N° du produit ABIN6221466

Détail du produit anti-SLAMF7 anticorps

Antigène: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Épitope: AA 23-226

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLAMF7 est non-conjugé

Application: Western Blotting (WB)

Séquence: SGPVKELVGS VGGAVTFPLK SKVKQVDSIV WTFNTTPLVT IQPEGGTIIV TQNRNRERVD FPDGGYSLKL SKLKKNDSGI YYVGIYSSSL QQPSTQEYVL HVYEHLSKPK VTMGLQSNKN GTCVTNLTCC MEHGEEDVIY TWKALGQAAN ESHNGSILPI SWRWGESDMT FICVARNPVS RNFSSPILAR KLCEGAADDP DSSM

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 23-226 of human SLAMF7 (NP_067004.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SLAMF7

Antigène: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Autre désignation: SLAMF7 (SLAMF7 Produits)

Synonymes: anticorps RGD1560190, anticorps SLAMF7, anticorps slaf7, anticorps 19A, anticorps CD319, anticorps CRACC, anticorps CS1, anticorps 19A24, anticorps 4930560D03Rik, anticorps SLAM family member 7, anticorps Slamf7, anticorps SLAMF7, anticorps slaf7

Sujet: SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed on the surface of NK cells, CD8+ T cells, activated B cells, and mature dendritic cells but not in promyelocytic, B-cell lines, or T-cell lines. In human NK cells, activated SLAMF7 transmits signals following association with the adaptor protein EAT-2 . In the absence of EAT-2, SLAMF7 potently inhibited natural killer cell function. It was also inhibitory in T cells, which are typically devoid of EAT-2. Thus, SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins.,SLAMF7,19A,CD319,CRACC,CS1,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,CD markers,SLAMF7

Poids moléculaire: 17 kDa/21 kDa/22 kDa/25 kDa/32 kDa/37 kDa

ID gène: 57823

UniProt: Q9NQ25