SLC8A1 anticorps (AA 250-520)

N° du produit ABIN6148050

Détail du produit anti-SLC8A1 anticorps

Antigène: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Épitope: AA 250-520

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC8A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: WVADRRLLFY KYVYKRYRAG KQRGMIIEHE GDRPSSKTEI EMDGKVVNSH VENFLDGALV LEVDERDQDD EEARREMARI LKELKQKHPD KEIEQLIELA NYQVLSQQQK SRAFYRIQAT RLMTGAGNIL KRHAADQARK AVSMHEVNTE VTENDPVSKI FFEQGTYQCL ENCGTVALTI IRRGGDLTNT VFVDFRTEDG TANAGSDYEF TEGTVVFKPG DTQKEIRVGI IDDDIFEEDE NFLVHLSNVK VSSEASEDGI LEANHVSTLA C

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 250-520 of human SLC8A1 (NP_066920.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SLC8A1

Antigène: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Autre désignation: SLC8A1 (SLC8A1 Produits)

Synonymes: anticorps NCX1, anticorps AI852629, anticorps AV344025, anticorps D930008O12Rik, anticorps Ncx1, anticorps Ncx, anticorps SLC8A1, anticorps ncx1n, anticorps solute carrier family 8 member A1, anticorps solute carrier family 8 (sodium/calcium exchanger), member 1, anticorps solute carrier family 8 (sodium/calcium exchanger), member 1b, anticorps sodium/calcium exchanger 1, anticorps SLC8A1, anticorps Slc8a1, anticorps slc8a1b, anticorps Tsp_07038

Sujet: In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.,SLC8A1,NCX1,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Calcium Signaling,Cardiovascular,Hypoxia,Heart,Contractility,SLC8A1

Poids moléculaire: 104 kDa/107 kDa/108 kDa

ID gène: 6546

UniProt: P32418

Pathways: Myometrial Relaxation and Contraction