SOS1 anticorps (AA 1034-1333)
Aperçu rapide pour SOS1 anticorps (AA 1034-1333) (ABIN6148283)
Antigène
Voir toutes SOS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1034-1333
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Séquence
- PLKSPGVRPS NPRPGTMRHP TPLQQEPRKI SYSRIPESET ESTASAPNSP RTPLTPPPAS GASSTTDVCS VFDSDHSSPF HSSNDTVFIQ VTLPHGPRSA SVSSISLTKG TDEVPVPPPV PPRRRPESAP AESSPSKIMS KHLDSPPAIP PRQPTSKAYS PRYSISDRTS ISDPPESPPL LPPREPVRTP DVFSSSPLHL QPPPLGKKSD HGNAFFPNSP SPFTPPPPQT PSPHGTRRHL PSPPLTQEVD LHSIAGPPVP PRQSTSQHIP KLPPKTYKRE HTHPSMHRDG PPLLENAHSS
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1034-1333 of human SOS1 (NP_005624.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SOS1 (Son of Sevenless Homolog 1 (SOS1))
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Autre désignation
- SOS1
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Sujet
- This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.,SOS1,GF1,GGF1,GINGF,HGF,NS4,Cancer,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,SOS1
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Poids moléculaire
- 36 kDa/152 kDa
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ID gène
- 6654
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UniProt
- Q07889
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Pathways
- Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Antigène
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