FGFR1 anticorps (C-Term)

N° du produit ABIN614919

Cet anticorps anti-FGFR1 Polyclonal Chèvre (ABIN614919) détecte spécifiquement FGFR1 dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain, Boeuf (Vache) et Chien.

Aperçu rapide pour FGFR1 anticorps (C-Term) (ABIN614919)

Antigène: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Reactivité: Humain, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-FGFR1 anticorps

Épitope: C-Term

Séquence: CLPRHPAQLA NGGLKR

Specificité: This antibody detects CD331 / FGFR1 (C-term).

Réactivité croisée (Details): Species reactivity (expected):Cow, DogSpecies reactivity (tested):Human

Purification: Immunoaffinity chromatography

Immunogène: Synthetic peptide from C-term of human FGFR1 Genename: FGFR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur FGFR1

Antigène: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Autre désignation: FGFR1

Sujet: The fibroblast growth factor receptor 1 belongs to the FGF Receptor subfamily. The full-length protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Ligand binding results in the activation of a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Various isoforms of FGFR1 have been identified that differ in structure and specificity. Defects in FGFR1 cause craniofacial abnormalities in diseases such as Pfeiffer syndrome and Jackson-Weiss syndrome.Synonyms: BFGFR, Basic fibroblast growth factor receptor 1, CEK, FGFBR, FLG, FLT-2, FLT2, Fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, HBGFR, N-sam, Proto-oncogene c-Fgr, bFGF-R-1

ID gène: 2260

NCBI Accession: NP_056934

UniProt: P11362

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins