TOPBP1 anticorps (AA 1253-1522)

N° du produit ABIN6149398

Détail du produit anti-TOPBP1 anticorps

Antigène: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Épitope: AA 1253-1522

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOPBP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: KIITIEETHE ELKKQYIFQL SSLNPQERID YCHLIEKLGG LVIEKQCFDP TCTHIVVGHP LRNEKYLASV AAGKWVLHRS YLEACRTAGH FVQEEDYEWG SSSILDVLTG INVQQRRLAL AAMRWRKKIQ QRQESGIVEG AFSGWKVILH VDQSREAGFK RLLQSGGAKV LPGHSVPLFK EATHLFSDLN KLKPDDSGVN IAEAAAQNVY CLRTEYIADY LMQESPPHVE NYCLPEAISF IQNNKELGTG LSQKRKAPTE KNKIKRPRVH

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1253-1522 of human TOPBP1 (NP_008958.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-TOPBP1 (ABIN6149398)

Wang, Wang, Xin, Wang, Wang, Xu, Jia, Yue, Wang, Song: "Two novel LRR-only proteins in Chlamys farreri: Similar in structure, yet different in expression profile and pattern recognition." dans: Developmental and comparative immunology, Vol. 59, pp. 99-109, (2017) (PubMed).

Détails sur TOPBP1

Antigène: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Autre désignation: TOPBP1 (TOPBP1 Produits)

Synonymes: anticorps RGD1562949, anticorps TOPBP1, anticorps cut5, anticorps F2P24.3, anticorps F2P24_3, anticorps meiosis defective 1, anticorps TOP2BP1, anticorps 1110031N14Rik, anticorps 2810429C13Rik, anticorps AI256758, anticorps D430026L04Rik, anticorps mKIAA0259, anticorps TopBP1-A, anticorps TopBP1-B, anticorps Xmus101, anticorps XtopBP, anticorps mus101, anticorps top2bp1, anticorps DNA topoisomerase II binding protein 1, anticorps topoisomerase (DNA) II binding protein 1, anticorps dna topoisomerase ii binding protein 1 (IC), anticorps transcription coactivator, anticorps DNA topoisomerase II binding protein 1 L homeolog, anticorps Topbp1, anticorps topbp1, anticorps TOPBP1, anticorps MEI1, anticorps topbp1.L

Sujet: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.,TOPBP1,TOP2BP1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Drug resistance,Topoisomerases,TOPBP1

Poids moléculaire: 170 kDa

ID gène: 11073

UniProt: Q92547

Pathways: Chromatin Binding