HLA-DRA anticorps

N° du produit ABIN6153414

Cet anticorps Souris Monoclonal détecte spécifiquement HLA-DRA dans FACS et IF. Il présente une réactivité envers Humain, Boeuf (Vache) et Cat.

Aperçu rapide pour HLA-DRA anticorps (ABIN6153414)

Antigène: HLA-DRA (HLA Class II DR alpha (HLA-DRA))

Reactivité: Humain, Boeuf (Vache), Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-DRA est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 169-1B5-2

Détail du produit anti-HLA-DRA anticorps

Fonction: Mouse Monoclonal anti-MHC-II (HLA-DRA) (169-1B5.2), Purified, BSA-free

Attributs du produit: This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Purification: Purified

Immunogène: Human peripheral blood leukocytes

Isotype: IgG2b kappa

Information d'application

Indications d'application: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Ramos, Daudi or HuT78 cells. Tonsil or lymph node

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Agent conservateur: Azide free

Détails sur HLA-DRA

Antigène: HLA-DRA (HLA Class II DR alpha (HLA-DRA))

Autre désignation: MHC-II (HLA-DRA)

Poids moléculaire: 36 kDa (? chain) and 27 kDa (? chain)

ID gène: 3122, 520048

UniProt: P01903

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response