Neurogranin anticorps (Internal Region)

N° du produit ABIN615919

Détail du produit anti-Neurogranin anticorps

Antigène: Neurogranin (NRGN)

Épitope: Internal Region

Reactivité: Humain, Souris, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurogranin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-KIKSGERGRK G

Specificité: This antibody recognizes Neurogranin. Reported variants represent identical protein: NP_006167.1, NP_001119653.1

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog) and Bovine.
Species reactivity (tested):Human, Mouse and Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_006167.1. Genename: NRGN

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Neurogranin

Antigène: Neurogranin (NRGN)

Autre désignation: Neurogranin (NRGN Produits)

Synonymes: anticorps RC3, anticorps hng, anticorps 0710001B06Rik, anticorps AI838505, anticorps NG, anticorps NG/RC3, anticorps Pss1, anticorps R75334, anticorps zgc:158686, anticorps neurogranin, anticorps neurogranin (protein kinase C substrate, RC3) b, anticorps NRGN, anticorps Nrgn, anticorps nrgnb

Sujet: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.Synonyms: Ng, Nrgn, Protein kinase C substrate 7.5 kDa protein, RC3

ID gène: 4900

NCBI Accession: NP_006167

UniProt: Q92686