VWF anticorps (CF®405S)
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- Antigène Voir toutes VWF Anticorps
- VWF (Von Willebrand Factor (VWF))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp VWF est conjugé à/à la CF®405S
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)
- Fonction
- Mouse Monoclonal anti-von Willebrand Factor (VWF635), CF405S Conjugate
- Attributs du produit
- von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant human vWF fragment
- Clone
- VWF635
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product VWF Anticorps primaire
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- Indications d'application
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Immunohistology (formalin)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1.0 μg/mL
- Immunoprecipitation 0.5-1 μg/500 μg protein lysate
- Optimal dilution for a specific application should be determined by user
- Commentaires
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HUVEC cells or Tonsil
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- VWF (Von Willebrand Factor (VWF))
- Autre désignation
- von Willebrand Factor (VWF Produits)
- Synonymes
- anticorps VWF, anticorps si:ch1073-474e24.1, anticorps F8VWF, anticorps VWD, anticorps 6820430P06Rik, anticorps AI551257, anticorps B130011O06Rik, anticorps C630030D09, anticorps von Willebrand factor, anticorps Von Willebrand factor, anticorps VWF, anticorps vwf, anticorps Vwf
- Sujet
- Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)
- Poids moléculaire
- 250 kDa
- ID gène
- 7450, 440848
- UniProt
- P04275
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