Transgelin anticorps (CF®640R)
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- Antigène Voir toutes Transgelin (TAGLN) Anticorps
- Transgelin (TAGLN)
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Reactivité
- Humain, Souris, Boeuf (Vache), Lapin, Porc
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Transgelin est conjugé à/à la CF®640R
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Fonction
- Mouse Monoclonal anti-Transgelin / SM22-alpha (TAGLN/247), CF640R Conjugate
- Attributs du produit
- This MAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant full-length human transgelin (TAGLN) protein.
- Clone
- TAGLN-247
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TAGLN Anticorps primaire
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- Indications d'application
- Flow Cytometry 0.5-1 μg/million cells/0.1 mLImmunofluorescence 1-2 μg/mL
- Commentaires
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U-2 OS, Hs68 or WI 38 cells. Colon carcinoma.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- Transgelin (TAGLN)
- Autre désignation
- Transgelin / SM22-alpha (TAGLN Produits)
- Synonymes
- anticorps MGC68550, anticorps sm22, anticorps smcc, anticorps tagln1, anticorps ws3-10, anticorps MGC107855, anticorps SM22, anticorps SMCC, anticorps TAGLN1, anticorps WS3-10, anticorps Sm22, anticorps Sm22a, anticorps Ws310, anticorps SM22A, anticorps zgc:153186, anticorps transgelin L homeolog, anticorps transgelin, anticorps tagln.L, anticorps tagln, anticorps LOC732906, anticorps TAGLN, anticorps tagl, anticorps LOC100009332, anticorps Tagln
- Poids moléculaire
- 22 kDa
- ID gène
- 6876, 410977
- UniProt
- Q01995
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