KRT17 anticorps (CF®594)
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- Antigène Voir toutes KRT17 Anticorps
- KRT17 (Keratin 17 (KRT17))
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Reactivité
- Humain, Rat, Boeuf (Vache), Porc, Chévre
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp KRT17 est conjugé à/à la CF®594
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Fonction
- Mouse Monoclonal anti-Cytokeratin 17 (KRT17/778), CF594 Conjugate
- Attributs du produit
- Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as ?epithelial stem cell? marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant full-length human KRT17 protein
- Clone
- KRT17-778
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product KRT17 Anticorps primaire
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- Indications d'application
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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T24 cells or Skin. Bladder or Cervix.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- KRT17 (Keratin 17 (KRT17))
- Autre désignation
- Cytokeratin 17 (KRT17 Produits)
- Synonymes
- anticorps K17, anticorps Krt1-17, anticorps PC, anticorps PC2, anticorps PCHC1, anticorps Ka17, anticorps KRT17, anticorps krt16, anticorps si:dkeyp-113d7.7, anticorps KRT14, anticorps keratin 17, anticorps keratin 17 L homeolog, anticorps keratin 17, type I, anticorps keratin, type I cytoskeletal 17, anticorps Krt17, anticorps KRT17, anticorps krt17, anticorps krt17.L, anticorps LOC100737113, anticorps LOC102177275
- Sujet
- K17, Keratin Type I Cytoskeletal 17, Keratin-17, KRT17, PCHC1
- Poids moléculaire
- 46 kDa
- ID gène
- 3872, 2785
- UniProt
- Q04695
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