CDX2 anticorps (AA 150-249) (CF®647)

N° du produit ABIN6182857

Détail du produit anti-CDX2 anticorps (CF®647)

Antigène: CDX2 (Caudal Type Homeobox 2 (CDX2))

Épitope: AA 150-249

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDX2 est conjugé à/à la CF®647

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Fonction: Mouse Monoclonal anti-CDX2 (CDX2/1690), CF647 Conjugate

Attributs du produit: The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human CDX2 protein fragment (aa150-249) (exact sequence is proprietary)

Clone: CDX2-1690

Isotype: IgG2a kappa

Information d'application

Indications d'application: ELISA 2-4 μg/mL for coating (order Ab without BSA)

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

HT29 cells or Colon Carcinoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur CDX2

Antigène: CDX2 (Caudal Type Homeobox 2 (CDX2))

Autre désignation: CDX2 (CDX2 Produits)

Synonymes: anticorps CDX2, anticorps MGC130987, anticorps cdx3-like, anticorps CDX-3, anticorps CDX3, anticorps CDX-2, anticorps Cdx-2, anticorps caudal type homeobox 2, anticorps caudal type homeobox 2 L homeolog, anticorps caudal type homeo box 2, anticorps CDX2, anticorps cdx2.L, anticorps Cdx2

Sujet: Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2

Poids moléculaire: 40 kDa

ID gène: 1045, 174249

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance