GP2 anticorps (AA 35-179) (CF®640R)

N° du produit ABIN6187071

Détail du produit anti-GP2 anticorps (CF®640R)

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Épitope: AA 35-179

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GP2 est conjugé à/à la CF®640R

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)

Fonction: Mouse Monoclonal anti-GP2 / ZAP75 (GP2/1551), CF640R Conjugate

Attributs du produit: GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human GP2 protein fragment (aa35-179) (exact sequence is proprietary)

Clone: GP2-1551

Isotype: IgG2b lambda

Information d'application

Indications d'application: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• ELISA For coating, order Ab without BSA
• Optimal dilution for a specific application should be determined by user

Commentaires:

PANC-1 cells. Pancreas

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur GP2

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Autre désignation: GP2 / ZAP75 (GP2 Produits)

Synonymes: anticorps ZAP75, anticorps 2310037I18Rik, anticorps AV060639, anticorps gp80, anticorps glycoprotein 2, anticorps glycoprotein 2 (zymogen granule membrane), anticorps GP2, anticorps Gp2

Classe de substances: Viral Protein

Sujet: Glycoprotein 2 (zymogen granule membrane), GP2, Pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75

Poids moléculaire: 59 kDa

ID gène: 2813, 53985

UniProt: P55259