ETS1 anticorps (AA 137-230) (CF®488A)

N° du produit ABIN6187620

Détail du produit anti-ETS1 anticorps (CF®488A)

Antigène: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Épitope: AA 137-230

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ETS1 est conjugé à/à la CF®488A

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Fonction: Mouse Monoclonal anti-ETS1-/ (ETS1/1282), CF488A Conjugate

Attributs du produit: ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator. The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells. ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human ETS1 fragment (aa137-230) (exact sequence is proprietary)

Clone: ETS1-1282

Isotype: IgG

Information d'application

Indications d'application: Flow cytometry 0.5-1 μg/million cells in 0.1 mL

• Immunohistology (formalin) 1-2 μg/mL
• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
• Western blotting 1-2 μg/mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

HepG2 and HeLa cells. Tonsil, Skin, Pancreas, Kidney and Lymphoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur ETS1

Antigène: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Autre désignation: ETS1- (ETS1 Produits)

Synonymes: anticorps ETS-1, anticorps EWSR2, anticorps ets1a-a, anticorps XE1-a, anticorps X1-c-ets-1a, anticorps ETS-1A, anticorps ETS-1B, anticorps TNIP1, anticorps c-ets-1, anticorps c-ets1, anticorps Ets-1, anticorps Etsoncb, anticorps Tpl1, anticorps ets1, anticorps ets, anticorps AI196000, anticorps AI448617, anticorps D230050P06, anticorps cb516, anticorps id:ibd1116, anticorps zgc:110573, anticorps XE1-b, anticorps ets-1, anticorps ets1-B, anticorps ETS proto-oncogene 1, transcription factor, anticorps v-ets avian erythroblastosis virus E26 oncogene homolog 1 S homeolog, anticorps v-ets avian erythroblastosis virus E26 oncogene homolog 1, anticorps v-ets erythroblastosis virus E26 oncogene homolog 1 (avian), anticorps E26 avian leukemia oncogene 1, 5' domain, anticorps v-ets avian erythroblastosis virus E26 oncogene homolog 1 L homeolog, anticorps ETS1, anticorps ets1.S, anticorps Ets1, anticorps ets1, anticorps ets1.L

Sujet: Avian erythroblastosis virus E26 (v ets) oncogene homolog 1, ETS1, EWSR2, p54, v-ets erythroblastosis virus E26 oncogene homolog 1

Poids moléculaire: 54 kDa

ID gène: 2113, 369438

UniProt: P14921