Tyrosinase-Related Protein 1 anticorps (CF®488A)
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- Antigène Voir toutes Tyrosinase-Related Protein 1 (TYRP1) Anticorps
- Tyrosinase-Related Protein 1 (TYRP1)
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Tyrosinase-Related Protein 1 est conjugé à/à la CF®488A
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Fonction
- Mouse Monoclonal anti-TRP1 (Tyrosinase Related Protein-1) (TYRP1/807), CF488A Conjugate
- Attributs du produit
- This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant full-length human TYRP1 protein
- Clone
- TYRP1-807
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product TYRP1 Anticorps primaire
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- Indications d'application
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Immunohistology formalin-fixed 2-4 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells or Melanoma.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- Tyrosinase-Related Protein 1 (TYRP1)
- Autre désignation
- (Tyrosinase Related Protein-1) (TYRP1 Produits)
- Synonymes
- anticorps CAS2, anticorps CATB, anticorps GP75, anticorps OCA3, anticorps TRP, anticorps TRP1, anticorps TYRP, anticorps b-PROTEIN, anticorps LOC397853, anticorps Trypsin, anticorps hm:zeh0659, anticorps tyrp1, anticorps zgc:100893, anticorps B, anticorps TYRP1, anticorps tyrp-1, anticorps TRP-1, anticorps Tyrp, anticorps b, anticorps brown, anticorps isa, anticorps tyrosinase related protein 1, anticorps protease, serine 1 L homeolog, anticorps tyrosinase-related protein 1b, anticorps tyrosinase-related protein 1, anticorps tyrosinase-related protein 1 L homeolog, anticorps tyrosinase-related protein 1a, anticorps TYRP1, anticorps prss1.L, anticorps tyrp1b, anticorps Tyrp1, anticorps tyrp1.L, anticorps tyrp1, anticorps LOC100136490, anticorps tyrp-1, anticorps tyrp1a
- Poids moléculaire
- 75 kDa
- ID gène
- 7306, 270279
- UniProt
- P17643
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