ZFPM1 anticorps (C-Term)

N° du produit ABIN6242705

Détail du produit anti-ZFPM1 anticorps

Antigène: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Épitope: AA 954-987, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZFPM1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ZFPM1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 954-987 amino acids from the C-terminal region of human ZFPM1.

Clone: RB51246

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur ZFPM1

Antigène: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Autre désignation: ZFPM1 (ZFPM1 Produits)

Synonymes: anticorps FOG, anticorps FOG1, anticorps ZC2HC11A, anticorps ZNF408, anticorps ZNF89A, anticorps Fog1, anticorps Xfog, anticorps fog, anticorps fog-1, anticorps fog1, anticorps FOG-1, anticorps si:dkey-20g6.1, anticorps si:dkey-38l12.1, anticorps ZNF469, anticorps ZFPM1, anticorps zinc finger protein, FOG family member 1, anticorps zinc finger protein, multitype 1, anticorps zinc finger protein, FOG family member 1 L homeolog, anticorps ZFPM1, anticorps Zfpm1, anticorps zfpm1.L, anticorps zfpm1

Sujet: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity).

Poids moléculaire: 104888

UniProt: Q8IX07