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CD7 anticorps

CD7 Reactivité: Humain FACS, IF Hôte: Souris Monoclonal HuLy-m2 unconjugated

N° du produit ABIN6251913

Fiche de données

Antigène Voir toutes CD7 Anticorps

CD7
Reactivité
186

25

10

10

7
Humain
Hôte
101

85

1

1
Souris
Anticorps secondaires appropriés
Clonalité
104

83

1
Monoclonal
Conjugué
66

19

15

14

10

8

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD7 est non-conjugé
Application
109

67

52

30

25

16

12

12

7

5

3

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF)

Purification

Protein G affinity chromatography

Immunogène

Human thymocytes were used as the immunogen for the CD7 antibody.

Clone

HuLy-m2

Isotype

IgG2a kappa

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Indications d'application

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Optimal dilution of the CD7 antibody should be determined by the researcher.

Restrictions

For Research Use only
Format

Liquid

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Aliquot and Store at -20C. Avoid freez-thaw cycles.
Antigène

CD7

Autre désignation

CD7 (CD7 Produits)

Synonymes

anticorps GP40, anticorps LEU-9, anticorps TP41, anticorps Tp40, anticorps CD7 molecule, anticorps CD7 antigen, anticorps Cd7 molecule, anticorps CD7, anticorps Cd7

Sujet

Recognizes a protein of 40  kDa, identified as CD7 (Workshop IV, Code T165). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

ID gène

924

UniProt

P09564

Pathways

Cell-Cell Junction Organization