ODC1 anticorps

N° du produit ABIN6252795

Détail du produit anti-ODC1 anticorps

Antigène: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ODC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Protein G affinity chromatography

Immunogène: Recombinant human protein was used as the immunogen for this ODC-1 antibody.

Clone: SPM565

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Western blot: 0.5-1 μg/mL

Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT (1)

Prediluted format: incubate for 30 min at RT (2)

The optimal dilution of the Ornithine Decarboxylase antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur ODC1

Antigène: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Autre désignation: Ornithine Decarboxylase (ODC1 Produits)

Synonymes: anticorps CG8721, anticorps Dmel\\CG8721, anticorps dodc1, anticorps odc, anticorps fc54f04, anticorps fi06d08, anticorps CHUNP6922, anticorps wu:fc54f04, anticorps wu:fi06d08, anticorps odc2, anticorps xODC1, anticorps xodc2, anticorps DDBDRAFT_0204020, anticorps DDBDRAFT_0237755, anticorps DDB_0204020, anticorps DDB_0237755, anticorps ODC, anticorps odc1, anticorps ODC1, anticorps Odc, anticorps odc1-a, anticorps Ornithine decarboxylase 1, anticorps ornithine decarboxylase 1, anticorps ornithine decarboxylase, anticorps diaminopimelate decarboxylase, anticorps Orn/DAP/Arg decarboxylase 2 domain-containing protein, anticorps Diaminopimelate decarboxylase, anticorps Ornithine decarboxylase, anticorps ornithine decarboxylase 1 L homeolog, anticorps ornithine decarboxylase, structural 1, anticorps Odc1, anticorps odc1, anticorps ODC1, anticorps odc, anticorps RR_RS04895, anticorps ASA_RS06380, anticorps LOC100232922, anticorps odc1.L, anticorps odc-1

Sujet: Recognizes a 53  kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

ID gène: 4953

UniProt: P11926