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TNFSF15 anticorps
TNFSF15
Reactivité: Humain
WB, IHC, IF, FACS
Hôte: Souris
Monoclonal
VEGI-1283
unconjugated
N° du produit ABIN6252818
Détail du produit anti-TNFSF15 anticorps
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Antigène
Voir toutes TNFSF15 Anticorps
TNFSF15
(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
Reactivité
Toutes les réactivités sur TNFSF15 Anticorps
Humain
Hôte
Toutes les hôtes sur TNFSF15 Anticorps
Souris
Clonalité
Toutes les clonalités sur TNFSF15 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers TNFSF15 Anticorps
Cet anticorp TNFSF15 est non-conjugé
Application
Tous les applications à travers TNFSF15 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
Purification
Protein G affinity chromatography
Immunogène
A full length human recombinant protein was used as the immunogen for this TL1A antibody.
Clone
VEGI-1283
Isotype
IgG1 kappa
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Information d'application
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Indications d'application
Flow Cytometry: 0.5-1 μg/10^6 cells IF: 1-2 μg/mL Western blot: 1-2 μg/mL IHC (FFPE): 1-2 μg/mL Titration of the TL1A antibody may be required for optimal performance.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Détails sur TNFSF15
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Antigène
TNFSF15
(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
Autre désignation
VEGI / TL1A (TNFSF15 Produits )
Synonymes
anticorps TTPAL, anticorps TL1, anticorps TL1A, anticorps VEGI, anticorps VEGI192A, anticorps Tl1, anticorps Tl1a, anticorps Vegi, anticorps tumor necrosis factor superfamily member 15, anticorps TNF superfamily member 15, anticorps tumor necrosis factor (ligand) superfamily, member 15, anticorps TNFSF15, anticorps Tnfsf15
Sujet
TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A has been reported as a marker of poor prognosis in breast cancer.
ID gène
9966
UniProt
O95150
Pathways
Positive Regulation of Endopeptidase Activity , Autophagy
Vus récemment
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