EGFR anticorps (C-Term)
Aperçu rapide pour EGFR anticorps (C-Term) (ABIN6254171)
Antigène
Voir toutes EGFR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- anti-ERBB1
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Séquence
- SHQISLDNPD YQQDFFPKEA KPNGIFKGST AENAEYLRVA PQSSEFIGA
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Specificité
- This antibody gives a positive signal in the following human (HaCat, SKOV3 and H69) whole cell lysates by Western blot.
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Attributs du produit
- Epidermal growth factor receptor
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Purification
- Epitope affinity purified
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Immunogène
- Purified recombinant peptide derived from within residues 1,162 aa to the C-terminus of human ERBB1 produced in E. coli.
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Isotype
- IgG
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Indications d'application
- WB:1:500-1:5,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
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Restrictions
- For Research Use only
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Buffer
- PBS, 20 % glycerol and 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- The antibody solution should be gently mixed before use.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Autre désignation
- ERBB1
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Sujet
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Goat polyclonal antibody to ERBB1. ERBB1 is a transmembrane glycoprotein that is a member of the protein kinase superfamily and a receptor for members of the epidermal growth factor family. It is a cell surface protein that binds to epidermal growth factor inducing receptor dimerization and tyrosine autophosphorylation and leading to cell proliferation. This receptor has been associated with cancer. Different protein isoforms encoded by multiple alternatively spliced transcript variants have been found for this gene.
EGFR, epidermal growth factor receptor, ERBB, HER1, mENA, NISBD2PIG61, antibody.
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Antigène
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