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HSP27 anticorps (pSer15)

Name: HSP27 anticorps (pSer15)
SKU: ABIN6256149
Price: 728.46 EUR
Availability: InStock

HSPB1 Reactivité: Humain, Rat, Souris WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated

Western blot analysis of HSP27 phosphorylation expression in UV treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (HSP27 anticorps (pSer15))

ABIN6267294 at 1/200 staining human kidney sections by IHC-P. (HSP27 anticorps (pSer15))

IHC

IF/ICC

3 images

(1 reference)

N° du produit ABIN6256149

Fiche de données

Antigène Voir toutes HSP27 (HSPB1) Anticorps

HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
Épitope
42

37

26

16

16

10

8

8

7

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer15
Reactivité
298

103

89

24

14

14

13

12

11

6

6

4

3

2

2

2

1
Humain, Rat, Souris
Hôte
236

66
Lapin
Anticorps secondaires appropriés
Clonalité
205

96
Polyclonal
Conjugué
137

23

17

13

12

8

7

7

7

7

7

7

4

4

4

4

4

4

4

3

3

3

3

2

1

1

1

1

1

1

1

1
Cet anticorp HSP27 est non-conjugé
Application
255

103

102

94

68

49

48

46

41

40

16

12

10

7

7

2

2

2

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité

Phospho-HSP27 (Ser15) Antibody detects endogenous levels of HSP27 only when phosphorylated at Serine 15.

Homologie

Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène

A synthesized peptide derived from human HSP27 around the phosphorylation site of Ser15.

Isotype

IgG

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HSPB1 Reactivité: Humain, Rat, Souris, Mouton, Singe, Poulet, Chimpanzé WB, IHC, IF, FACS, ISt, StM Hôte: Souris Monoclonal G3-1 unconjugated

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anti-Heat Shock 27kDa Protein 1 (HSPB1) antibody
HSPB1 Reactivité: Humain WB, IHC, IF, FACS, ICC Hôte: Lapin Polyclonal unconjugated

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anti-Heat Shock 27kDa Protein 1 (HSPB1) antibody (HRP)
HSPB1 Reactivité: Humain WB, IHC, IF, FACS, IP, ICC Hôte: Souris Monoclonal 8A7 HRP

Indications d'application

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

PBS, pH 7.4,50 % glycerol.

Stock

-20 °C

Date de péremption

12 months
Xia, Yao, Tang, Xiao, Yang, Zhou: "Isobaric Tags for Relative and Absolute Quantitation (iTRAQ)-Based Proteomic Analysis of Hugan Qingzhi and Its Protective Properties against Free Fatty Acid-Induced L02 Hepatocyte Injury." dans: Frontiers in pharmacology, Vol. 8, pp. 99, (2017) (PubMed).
Antigène

HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Autre désignation

HSPB1 (HSPB1 Produits)

Synonymes

anticorps CMT2F, anticorps HMN2B, anticorps HS.76067, anticorps HSP27, anticorps HSP28, anticorps Hsp25, anticorps SRP27, anticorps 27kDa, anticorps Hsp27, anticorps cb153, anticorps cb660, anticorps hsp1, anticorps hsp25, anticorps hsp27, anticorps id:ibd2821, anticorps sb:cb660, anticorps zgc:103437, anticorps HSPB1, anticorps cmt2f, anticorps hs.76067, anticorps hsp28, anticorps heat shock protein family B (small) member 1, anticorps heat shock protein 1, anticorps heat shock protein, alpha-crystallin-related, 1, anticorps heat shock protein family B (small) member 1 L homeolog, anticorps HSPB1, anticorps Hspb1, anticorps hspb1, anticorps hspb1.L

Sujet

Description: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).
Gene: HSPB1

Poids moléculaire

27kDa

ID gène

3315

UniProt

P04792

Pathways

Signalisation MAPK, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling