GTF2H1 anticorps (N-Term)

N° du produit ABIN6256996

Détail du produit anti-GTF2H1 anticorps

Antigène: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF2H1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: TF2H1 Antibody detects endogenous levels of total TF2H1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TF2H1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur GTF2H1

Antigène: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Autre désignation: GTF2H1 (GTF2H1 Produits)

Synonymes: anticorps 62kDa, anticorps AW743425, anticorps AW822074, anticorps BTF2 p62, anticorps C77871, anticorps p62, anticorps GTF2H1, anticorps BTF2, anticorps P62, anticorps TFB1, anticorps TFIIH, anticorps gtf2h1, anticorps MGC53309, anticorps btf2, anticorps tfiih, anticorps CG8151, anticorps Dmel\\CG8151, anticorps Dmp62, anticorps TfBl, anticorps l(2)06949, anticorps l(2)06950, anticorps zgc:92126, anticorps general transcription factor IIH subunit 1, anticorps general transcription factor II H, polypeptide 1, anticorps general transcription factor IIH subunit 1 L homeolog, anticorps Transcription factor B1, anticorps general transcription factor IIH, polypeptide 1, anticorps GTF2H1, anticorps Gtf2h1, anticorps gtf2h1.L, anticorps gtf2h1, anticorps Tfb1

Sujet:

Description: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.

Gene: GTF2H1

Poids moléculaire: 57 kDa

ID gène: 2965

UniProt: P32780

Pathways: Réparation de l'ADN