ELL2 anticorps (Internal Region)

N° du produit ABIN6257461

Détail du produit anti-ELL2 anticorps

Antigène: ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELL2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: ELL2 Antibody detects endogenous levels of total ELL2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ELL2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur ELL2

Antigène: ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))

Autre désignation: ELL2 (ELL2 Produits)

Synonymes: anticorps cb244, anticorps fb78f03, anticorps sb:cb244, anticorps im:3814960, anticorps wu:fb78f03, anticorps xell2, anticorps MGC82755, anticorps ELL2, anticorps elongation factor for RNA polymerase II 2, anticorps elongation factor, RNA polymerase II, 2, anticorps elongation factor, RNA polymerase II 2 S homeolog, anticorps elongation factor, RNA polymerase II 2, anticorps elongation factor RNA polymerase II 2, anticorps ELL2, anticorps ell2, anticorps ell2.S, anticorps Ell2

Sujet:

Description: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression.

Gene: ELL2

Poids moléculaire: 72 kDa

ID gène: 22936

UniProt: O00472