HINT1 anticorps (Internal Region)

N° du produit ABIN6257885

Détail du produit anti-HINT1 anticorps

Antigène: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HINT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: HINT1 Antibody detects endogenous levels of total HINT1.

Homologie: Pig,Zebrafish,Bovine,Horse,Rabbit,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HINT1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur HINT1

Antigène: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Autre désignation: HINT1 (HINT1 Produits)

Synonymes: anticorps hint, anticorps pkci-1, anticorps prkcnh1, anticorps HINT, anticorps NMAN, anticorps PKCI-1, anticorps PRKCNH1, anticorps AA673479, anticorps Hint, anticorps Ipk1, anticorps Pkci, anticorps Prkci, anticorps zgc:103764, anticorps CHPKCI, anticorps HINTZ, anticorps PKCIZ, anticorps histidine triad nucleotide binding protein 1, anticorps histidine triad nucleotide binding protein 1 S homeolog, anticorps histidine triad nucleotide binding protein 1-Z, anticorps Histidine triad nucleotide-binding protein 1, anticorps HINT1, anticorps hint1, anticorps Hint1, anticorps hint1.S, anticorps HINT1Z, anticorps hint-1

Sujet:

Description: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

Gene: HINT1

Poids moléculaire: 28 kDa

ID gène: 3094

UniProt: P49773