TP53BP2 anticorps (Internal Region)
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- Antigène Voir toutes TP53BP2 Anticorps
- TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TP53BP2 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- ASPP2 Antibody detects endogenous levels of total ASPP2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human ASPP2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product TP53BP2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))
- Autre désignation
- TP53BP2 (TP53BP2 Produits)
- Synonymes
- anticorps 53BP2, anticorps ASPP2, anticorps BBP, anticorps P53BP2, anticorps PPP1R13A, anticorps TP53BP2, anticorps AI746547, anticorps Tp53bp2, anticorps X98550, anticorps Trp53bp2, anticorps wu:fa09h08, anticorps wu:fb04e08, anticorps zgc:85720, anticorps tumor protein p53 binding protein 2, anticorps tumor protein p53 binding protein 2 L homeolog, anticorps tumor protein p53 binding protein, 2b, anticorps transformation related protein 53 binding protein 2, anticorps tumor protein p53 binding protein, 2, anticorps tumor protein p53 binding protein, 2a, anticorps TP53BP2, anticorps tp53bp2.L, anticorps tp53bp2, anticorps tp53bp2b, anticorps Trp53bp2, anticorps Tp53bp2, anticorps tp53bp2a
- Sujet
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Description: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
Gene: TP53BP2
- Poids moléculaire
- 170 kDa
- ID gène
- 7159
- UniProt
- Q13625
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