KCNQ5 anticorps (C-Term)

N° du produit ABIN6258866

Détail du produit anti-KCNQ5 anticorps

Antigène: KCNQ5 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNQ5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: KCNQ5 Antibody detects endogenous levels of total KCNQ5.

Homologie: Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human KCNQ5, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur KCNQ5

Antigène: KCNQ5 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5))

Autre désignation: KCNQ5 (KCNQ5 Produits)

Synonymes: anticorps KCNQ5, anticorps si:dkey-29l6.1, anticorps Kcnq5l, anticorps Kv7.5, anticorps 7730402H11, anticorps 9230107O05Rik, anticorps AA589396, anticorps D1Mgi1, anticorps potassium voltage-gated channel subfamily Q member 5, anticorps potassium voltage-gated channel, KQT-like subfamily, member 5a, anticorps potassium voltage-gated channel, KQT-like subfamily, member 5, anticorps potassium voltage-gated channel, subfamily Q, member 5, anticorps KCNQ5, anticorps kcnq5a, anticorps Kcnq5

Sujet:

Description: Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. Therefore, it is important in the regulation of neuronal excitability. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. As the native M-channel, the potassium channel composed of KCNQ3 and KCNQ5 is also suppressed by activation of the muscarinic acetylcholine receptor CHRM1.

Gene: KCNQ5

Poids moléculaire: 100 kDa

ID gène: 56479

UniProt: Q9NR82